3071 Cell Survival in Corneal Endothelial Dystrophies
نویسندگان
چکیده
منابع مشابه
Genetic Perspective of Corneal Endothelial Dystrophies
The corneal endothelium serves primarily in maintaining stromal deturgescence which is essential for transparency of cornea. Any disturbance in its function leads to stromal edema which in turn reduces vision. The genetically heterogeneous nature of four different kinds of corneal endothelial dystrophies represents the involvement of diverse set of genes. Until now, only few genes were identifi...
متن کاملFuchs' Endothelial and Myotonic Dystrophies: Corneal Dystrophy in Myotonic Patients.
We read with great interest the article by Mootha et al. concerning a possible correlation between Fuchs’ endothelial corneal dystrophy (FECD) and myotonic dystrophy (MD). We thank the authors because, among the studies we made trying to understand the reason of low intraocular pressure in patients with MD, they cited one study we published in 2010 where we examined the endothelial cells charac...
متن کاملCorneal dystrophies
The term corneal dystrophy embraces a heterogenous group of bilateral genetically determined non-inflammatory corneal diseases that are restricted to the cornea. The designation is imprecise but remains in vogue because of its clinical value. Clinically, the corneal dystrophies can be divided into three groups based on the sole or predominant anatomical location of the abnormalities. Some affec...
متن کامل2316 Changes in the human corneal keratocyte and endothelial cell density during aging and during corneal dystrophies
i?&bQ!k A total of 200 normal human corneas (age: 6 months 92 years) were collected among bodies intended for autopsy. Pathological comeal buttons were obtained from patients undergoing penetrating keratoplasty for keratoconus, Fuchs’ end&&xl dyamphy, postcataract endothelial dystrophy, and others. The keratocyte density was assessed using a quantitative meawem eat of the stmmal DNA-content. Th...
متن کاملPredicting endothelial cell loss and long-term corneal graft survival.
PURPOSE To evaluate a biexponential decay model for describing the loss of corneal endothelial cells with age as well as the increased loss of cells after cataract surgery and penetrating keratoplasty. METHODS Data from previous studies were identified and the sum of two exponentials, d = p. exp(-at) + q. exp(-bt) (where d is cell density at time t, p and q are constants the sum of which is e...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Clinical and Translational Science
سال: 2019
ISSN: 2059-8661
DOI: 10.1017/cts.2019.12